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Discover how comprehensive genomic profiling from Foundation Medicine may help open up treatment possibilities for you1–3

Your cancer’s mutations

Cancer occurs due to changes in DNA and/or RNA called mutations that affect the way your cells work and grow.4,5

Each person’s cancer is unique because mutations differ in type and number and between cancer types.6,7

Even if you have the same type of cancer as someone else, your mutations may differ to theirs, and you may need
different treatment.6–8

Your care team might suggest testing your cancer to find out what mutations you have in your DNA and/or RNA.

If certain mutations are found in your cancer cells your doctor may be able to give you a more precise treatment based on this finding. There might be cases where either no relevant mutation is found or no targeted treatment option is available for the mutation that has been identified. This is also valuable information, supporting further treatment planning.6–11

Precision medicine increases the likelihood you will find a targeted therapy, which may improve your chance of responding well or could mean that you experience fewer side effects.3

Knowing the mutations in your cancer can help you and your doctor understand your treatment options and may help to personalise your treatment.6–11

Learn more about cancer and available treatment options

Discuss with your doctor whether Foundation Medicine testing could be right for you.

What is comprehensive genomic profiling (CGP)?

Genomic testing encompasses single biomarker testing, hotspot testing and comprehensive genomic profiling. They all test your cancer sample for mutations but work in different ways.

Comprehensive genomic profiling is being performed by using an advanced technology called Next Generation Sequencing (NGS). With NGS, we are able to screen large amounts of genes in parallel which will speed up the time and be more cost effective compared with old technology like Sanger Sequencing.34

Comprehensive Genomic Profiling looks for all types of known genomic alterations across all of the cancer-related genes in a single sample of tumour tissue or blood.

*All types of genomic alterations: base substitutions, copy number alterations, rearrangements, insertions and deletions, as well as tumour mutational burden (TMB) and microsatellite instability (MSI) status.

Foundation Medicine's comprehensive genomic profiling may improve your chance of finding a personalised treatment

Discuss with your doctor whether Foundation Medicine testing could be right for you.

 

 

Our services

Foundation Medicine offers a high-quality portfolio of comprehensive genomic profiling services that can help you and your doctor better understand your treatment options.1,14–17

There are different tests available for patients with different types of cancer.

FoundationOne®CDx, FoundationOne®Liquid CDx and FoundationOne®Heme search for multiple mutations in your cancer sample to increase your chances of finding a more precise treatment and help personalise your cancer treatment
plan.1,2,13–17,21–32

FoundationOne CDx and FoundationOne Liquid CDx are for patients with all types of solid tumours, e.g. lung, prostate or breast cancer.14,15

FoundationOne Heme is for patients with sarcoma and blood cancers such as leukaemia.17

*FoundationOne Heme for blood cancers is NOT AVAILABLE for Malaysia

Your care team will receive a comprehensive report which will include the details on your tumour profile and may identify therapies and clinical trials for you to discuss together.6–11,33

The following materials provide further information about FoundationOne CDx, FoundationOne Liquid CDx and FoundationOne Heme:

FoundationOne Heme brochure for patients
with blood cancers and sarcomas > 

FoundationOne Heme for blood cancers is NOT AVAILABLE for Malaysia

Discuss with your doctor whether Foundation Medicine testing could be right for you.